A wrinkle, also medically referred as a rhytide, is an appearing fold, ridge, or crease in our skin as a result of aging processes such as glycation, habitual sleeping positions, loss of body mass, habitual facial expressions, sun damage, smoking, and loss of hydration.
Clinically speaking, the development of facial wrinkles is a kind of fibrosis of the skin, and incorrect repairs of injured elastic fibers and collagen fibers. Due to repeating extensions and compressions of our skin, the extracellular fibers in derma is constantly injured. However, the repairing process cannot guarantee the complete restoration of broken elastic fibers and collagen fibres, thus generating “long” collagen fibers. The accumulation of “long” collagen fibers causes looseness and stiffness in the skin, and as a consequence, a noticeable fold of the skin appears. Similarly, “short” collagen fibers are generated when “long” collagen fibers are broken in a compressed state, and as a consequence, a “long” fiber in a folded state becomes permanent. These noticeable small folds are commonly known as permanent wrinkles in our skin.
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